Dr. Sharp Awarded 5-Year NIH R01 Grant!

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Will Sharp, MD and his lab members were recently awarded a 5 year NIH R01 award totaling $1,975,000 in July 2016. The grant titled “Pharmacological induced torpor/hypothermia as a novel therapy for improving post-cardiac arrest outcomes” uses cellular, tissue, and animal models to investigate the effects of hypothermia/cooling in the setting of cellular ischemia and cardiac arrest. Unlike current clinical strategies of physically cooling patients after cardiac arrest, Dr. Sharp’s grant focuses on developing agents that decrease patient’s metabolic rate in order to induce hypothermia. This work will hopefully lead to new treatment strategies for post-cardiac arrest patients. This grant builds on Dr. Sharp’s prior NIH K08 award and an award from the University of Chicago’s Women’s Board.